Nico Andreas Friedrich

Dr.-Ing. Nico Leister

  • Postanschrift: Kaiserstr. 12
    Liefer- und Besucheranschrift: Gotthard-Franz-Straße 3
    Geb. 50.31, 4. OG
    D-76131 Karlsruhe

About myself

During my studies of chemical engineering at the Karlsruhe Institute of Technology, I dealt with various aspects of chemical processes, measurement methods and food functionality. I completed my master studies with a thesis on the topic of “process-related material properties of protein-starch systems“. At the end of 2017, I started my doctoral studies as part of my work as a research assistant in the Food Process Engineering group.

Research focus

My research focuses on the characterization and stabilization of water in oil in water (W/O/W) double emulsions. One big challenge is to describe instability mechanisms causing the loss of the inner water phase, such as coalescence and diffusion. Those effects depend strongly on the formulation of the emulsions. For this purpose, the interactions between lipophilic and hydrophilic emulsifiers at W/O and O/W interfaces and their influence on the stability are measured.


The double emulsions are prepared in a two-step-process. Therefore, I use different emulsification techniques (e.g. Rotor-Stator-Systems, High-Pressure-Emulsification and Membrane-Emulsification). To characterize the double emulsions’ structural and functional properties, I mainly use laser diffraction and microsopy. In addition, I investigate the interfacial properties and rheological behavior of double emulsions. Furthermore, I observe coalescence and diffusion processes with a high-speed camera on single droplets in double emulsions.

Aktuelle Angebote für Bachelor- und Masterarbeiten


Possibilities and limits of modeling cavitation in high-pressure homogenizers – a validation study
Rütten, E.; Leister, N.; Karbstein, H. P.; Håkansson, A.
2024. Chemical Engineering Science, 283, Art.-Nr.: 119405. doi:10.1016/j.ces.2023.119405
Influence of Rapeseed Oil on Extruded Plant-Based Meat Analogues: Assessing Mechanical and Rheological Properties
Saavedra Isusi, G. I.; Pietsch, V.; Beutler, P.; Hoehne, S.; Leister, N.
2023. Processes, 11 (7), Art.-Nr.: 1871. doi:10.3390/pr11071871
Lego®-Inspired Glass Capillary Microfluidic Device: A Technique for Bespoke Microencapsulation of Phase Change Materials
Parvate, S.; Vladisavljevic, G. T.; Leister, N.; Bolognesi, G.; Baiocco, D.; Zhang, Z.; Spyrou, A.; Chattopadhyay, S.
2023. ACS applied materials & interfaces, 15 (13), 17195–17210. doi:10.1021/acsami.3c00281
A comprehensive methodology to study double emulsion stability
Leister, N.; Götz, V.; Jan Bachmann, S.; Nachtigall, S.; Hosseinpour, S.; Peukert, W.; Karbstein, H.
2023. Journal of Colloid and Interface Science, 630 (B), 534–548. doi:10.1016/j.jcis.2022.10.119
Monitoring of Osmotic Swelling Induced Filling Degree Changes in WOW Double Emulsions Using Raman Technologies
Hufnagel, T.; Leister, N.; Stoy, R.; Rädle, M.; Karbstein, H. P.
2023. Chemosensors, 11 (4), Art.-Nr.: 206. doi:10.3390/chemosensors11040206
Novel glass capillary microfluidic devices for the flexible and simple production of multi-cored double emulsions
Leister, N.; Vladisavljević, G. T.; Karbstein, H. P.
2022. Journal of colloid and interface science, 611, 451–461. doi:10.1016/j.jcis.2021.12.094


Phasenübergänge emulgierter Fette und deren Einfluss auf Instabilitätsvorgänge und die Makrostruktur kristalliner Dispersionen
Reiner, J.; Leister, N. R.; Karbstein, H. P.
2023, March 14. Jahrestreffen der DECHEMA-Fachgruppen Hochdruckverfahrenstechnik (2023), Bochum, Germany, March 13–15, 2023
Emulgatoren in Doppelemulsionen und deren Einfluss auf die Stabilität gegen die verschiedenen Koaleszenzpfade
Leister, N.; Karbstein, H.
2023, March. Jahrestreffen der DECHEMA-Fachgruppen Kristallisation, Grenzflächenbestimmte Systeme und Prozesse und Mechanische Flüssigkeitsabtrennung (2023), Frankfurt am Main, Germany, March 9–10, 2023
Coalescence phenomena in double emulsions examined via models with different droplet sizes
Leister, N.; Karbstein, H. P.
2022, June 29. 18th European Student Colloid Conference (ESC 2022), Szeged, Hungary, June 26–30, 2022
Instabilitätsmechanismen in Doppelemulsionen aufgezeigt am Beispiel mikrofluidisch hergestellter Tropfen
Leister, N.; Vladisavljević, G. T.; Karbstein, H. P.
2022, March 11. Jahrestreffen der ProcessNet-Fachgruppen Lebensmittelverfahrenstechnik und Trocknungstechnik (2022), Frankfurt am Main, Germany, March 10–11, 2022
Diffusion and interaction of emulsifiers in double emulsions and their effect on the release of encapsulated substances
Leister, N.; Karbstein, H. P.
2021, September 6. 29th European Conference on Information Systems (ECIS 2021), Online, June 14–16, 2021
Stabilisierung von Doppelemulsionen: Untersuchung der Emulgatorwechselwirkungen anhand von Einzeltropfenexperimenten
Leister, N.; Karbstein, H. P.
2021, March 12. Jahrestreffen der ProcessNet-Fachgruppen Lebensmittelverfahrenstechnik, Mischvorgänge, Grenzflächenbestimmte Systeme und Prozesse (2021), Online, March 11–12, 2021
Encapsulation in double emulsions Analysis of stability mechanisms = Analyse der Stabilisierungsmechanismen in Doppelemulsionen
Nachtigall, S.; Holtze, C.; Laurenzis, A.; Bachmann, S.; Oetter, G.; Runge, F.; Götz, V.; Hosseinpour, S.; Peukert, W.; Leister, N.; Karbstein, H. P.
2020, September 22. 10./34. ProcessNet-Jahrestagung und DECHEMA-Jahrestagung der Biotechnologen (2020), Online, September 21–24, 2020
Encapsulation in double emulsions - Fundamental analysis of stabilitys
Nachtigall, S.; Holtze, C.; Laurenzis, A.; Bachmann, S.; Vranceanu, M.; Oetter, G.; Runge, F.; Götz, V.; Hosseinpour, S.; Peukert, W.; Leister, N.; Karbstein, H. P.
2019, June 25. Formula X (2019), Manchester, United Kingdom, June 24–27, 2019
Influence of the hydrophilic emulsifier on the coalescence time in double emulsions
Leister, N.; Neumann, S.; Schaaf, U. van der; Karbstein, H. P.
2019, June 20. 17th European Student Colloid Conference (ESC 2019), Varna, Bulgaria, June 18–22, 2019
Modellhafte Untersuchung physikalischer Instabilitätsphänomene in W/O/W Doppelemulsionen
Leister, N. R.; Neumann, S. M.; Schaaf, U. S. van der; Karbstein, H. P.
2019, March 13. Jahrestreffen der ProcessNet-Fachgruppen Lebensmittelverfahrenstechnik, Mischvorgänge, Grenzflächenbestimmte Systeme und Prozesse (2019), Bamberg, Germany, March 12–13, 2019